IACUC Ongoing Training

Dr. A Nonymouse wants to add retro-orbital bleeds to their mouse protocol. Dr. Nonymouse is eager to begin conducting the procedure as soon as possible. Dr. Nonymouse was thrilled to see that there is an approved animal procedure (AAP) that outlines Retro-orbital Bleeds for Mice.  What are the steps they must complete prior to initiating this procedure on the animals on their protocol?  

A. Prior to conducting the procedure, Dr. Nonymouse must submit an amendment to add the AAP to their protocol. Once they have submitted the amendment, they can begin completing the procedure.  

B. Nothing. The AAP is an approved animal procedure so no further steps are required. 

C. Prior to conducting the procedure, Dr. Nonymouse must submit an amendment to add the AAP to their protocol. To add the AAP to the protocol, they must complete the Protocol Instructions outlined on the AAP. Dr. Nonymouse must wait until the amendment is approved by the Committee prior to initiating these procedures. 

To view quiz question answers and learner feedback, please click the “Ongoing Training Answers and Learner Feedback” tab toward the top of the page.

Dr. A Nonymouse wants to add retro-orbital bleeds to their mouse protocol. Dr. Nonymouse is eager to begin conducting the procedure as soon as possible. Dr. Nonymouse was thrilled to see that there is an approved animal procedure (AAP) that outlines Retro-orbital Bleeds for Mice.  What are the steps they must complete prior to initiating this procedure on the animals on their protocol?  

A. Prior to conducting the procedure, Dr. Nonymouse must submit an amendment to add the AAP to their protocol. Once they have submitted the amendment, they can begin completing the procedure.  

B. Nothing. The AAP is an approved animal procedure so no further steps are required. 

C. Prior to conducting the procedure, Dr. Nonymouse must submit an amendment to add the AAP to their protocol. To add the AAP to the protocol, they must complete the Protocol Instructions outlined on the AAP. Dr. Nonymouse must wait until the amendment is approved by the Committee prior to initiating these procedures. 

Learner Feedback: The correct answer is C. AAPs are standard procedures reviewed by the IACUC with specific protocol instructions to minimize data entry and streamline protocol review for laboratories wishing to utilize AAPs. Although an AAP is a standard procedure reviewed and approved by the IACUC, it cannot be performed until it is reviewed and approved in context of the protocol to which the animals are assigned. Therefore, A and B are incorrect as they have not been approved within the protocol the laboratory is intending to use. Prior to conducting the procedure, Dr. Nonymouse must submit an amendment to add the AAP to their protocol by following the Protocol Instructions outlined on the AAP and await approval. Please note that each AAP specifies where and how it should be cited in your Approved Animal Study Protocol (ASP). Once the amendment is approved, the procedure has been added to the protocol and can now be conducted. Ensure to document training and competency in your in-lab training by a senior or experienced lab member in the procedure to be performed. Some AAPs have specific training requirements, please ensure to review and adhere to those requirements. Please visit the AAP website to see what procedures are available that could be utilized for your research, minimizing the data entry required in the protocol.